- Framework of problems / Rigourous
- Inadequate analysis of heterogeneity
- Dissemination bias in systematic reviews of animal research: a systematic review
Ref ID | 555 |
First Author | K. F. Mueller |
Journal | PLOS ONE |
Year Of Publishing | 2014 |
URL | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116016 |
Keywords |
Animal studies Publication bias Heterogeneity Pre-specification Low reporting quality Low methodological quality |
Problem(s) |
Low reporting or methodological quality (OTHER GUIDANCE) No quality assessment undertaken or reported Lack of prespecification in eligibility criteria Poor consideration of publication bias Inadequate analysis of heterogeneity Individual study characteristics not reported sufficiently |
Number of systematic reviews included | 512 |
Summary of Findings | Only 59% of included systematic reviews clearly defined inclusion and exclusion criteria; just over half (51%) displayed a list or flow diagram of the included studies; 24% of included reviews did not report how many studies were included. The majority of the included systematic reviews and meta-analyses of animal studies did not assess methodological quality of included studies (71%), or assess heterogeneity (81%), or publication bias (87%). |
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Not Applicable |
Are the methods of the article described in enough detail to replicate the study? | Yes |