- Framework of problems / Objective
- Inflexible methods to complex questions
- Outcomes in systematic reviews of complex interventions never reached “high” GRADE ratings when compared with those of simple interventions
| Ref ID | 604 |
| First Author | A. Movsisyan |
| Journal | JOURNAL OF CLINICAL EPIDEMIOLOGY |
| Year Of Publishing | 2016 |
| URL | https://www.jclinepi.com/article/S0895-4356(16)30026-9/abstract |
| Keywords |
Imprecision General medical |
| Problem(s) |
Inflexible methods to complex questions |
| Number of systematic reviews included | 40 |
| Summary of Findings | The quality of evidence never reached ‘‘high’’ GRADE ratings for the outcomes of complex intervention reviews, compared to simple intervention reviews. Quality ratings were commonly downgraded in the Risk of Bias assessment, particularly for lack of participant and personnel blinding; high levels of heterogeneity, and the study design |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Not Applicable |
| Are the methods of the article described in enough detail to replicate the study? | Yes |