- Framework of problems / Objective
- Failure to define clinically meaningful outcomes
- Strong heterogeneity of outcome reporting in systematic reviews
| Ref ID | 619 |
| First Author | B. Sautenet |
| Journal | JOURNAL OF CLINICAL EPIDEMIOLOGY |
| Year Of Publishing | 2016 |
| URL | https://www.jclinepi.com/article/S0895-4356(16)00039-1/fulltext |
| Keywords |
Multiplicity Heterogeneity Pre-specification Nephrology Outcomes |
| Problem(s) |
Inadequate analysis of heterogeneity Multiplicity of outcomes and lack of pre-specification for outcome reporting Failure to define clinically meaningful outcomes |
| Number of systematic reviews included | 66 |
| Summary of Findings | From a total of 609 outcomes extracted, 20 outcomes related to renoprotection and were meta-analysed only 7.6% of the systematic reviews assessed. A core outcome set was concluded to be required in order to prevent research waste. |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Not Applicable |
| Are the methods of the article described in enough detail to replicate the study? | No |