- Framework of problems / Objective
- High risk of bias (ROBIS)
- Risk of Bias and Quality of Reporting in Colon and Rectal Cancer Systematic Reviews Cited by National Comprehensive Cancer Network Guidelines
| Ref ID | 72 |
| First Author | C. Wayant |
| Journal | JOURNAL OF GENERAL INTERNAL MEDICINE |
| Year Of Publishing | 2020 |
| URL | https://pubmed.ncbi.nlm.nih.gov/31950401/ |
| Keywords |
Protocols Oncology Pre-specification |
| Problem(s) |
No registered or published protocol Lack of prespecification in eligibility criteria High risk of bias (ROBIS) |
| Number of systematic reviews included | 63 |
| Summary of Findings | Using ROBIS, only 3 (4.8%) of the included 63 systematic reviews were judged with low risk of bias, 35 (55.6%) systematic reviews were judged with unclear risk of bias, and 25 (39.7%) systematic reviews were judged with high risk of bias. Across all systematic reviews, the individual bias domains at the highest risk of bias were domains 1 (protocol and eligibility criteria) and 2 (methods to identify and select studies). Across all studies, the median adherence to PRISMA was 74.1% (IQR 69.2–80.0%), corresponding to approximately 20 of 27 items. |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Not Applicable |
| Are the methods of the article described in enough detail to replicate the study? | Yes |