- Framework of problems / Rigourous
- Incorrect interpretation or statistical inference error from meta-analysis
- Critical thinking about three meta-analyses: can vitamin D alone or with calcium prevent fractures?
| Ref ID | 779 |
| First Author | H. Fan |
| Journal | CURRENT MEDICAL RESEARCH AND OPINION |
| Year Of Publishing | 2020 |
| URL | https://www.tandfonline.com/doi/full/10.1080/03007995.2019.1687432 |
| Keywords |
Orthopaedic Inference Vitamins and supplements Non-Cochrane reviews |
| Problem(s) |
Intervention not described / defined Ignores setting or context of included studies which limits review applicability Incorrect interpretation or statistical inference error from meta-analysis |
| Number of systematic reviews included | 3 |
| Summary of Findings | The discussion piece highlights various concerns over the conduct of two of three systematic reviews on vitamin D supplementation on fracture prevention with opposing conclusions published between 2007 to 2018. Concerns include a failure to appropriately define target populations and interventions for included studies and failure to appropriately interpret the conditions under which the conclusions of the review were accurate. |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Not Applicable |
| Are the methods of the article described in enough detail to replicate the study? | No |