Reporting and Handling of Missing Participant Data in Systematic Reviews of Kidney Transplant Studies

Ref ID 826
First Author P. Budhiraja
Journal TRANSPLANTATION
Year Of Publishing 2021
URL https://journals.lww.com/transplantjournal/Fulltext/2021/08000/Reporting_and_Handling_of_Missing_Participant_Data.17.aspx
Keywords • Cochrane
• Non-Cochrane reviews
• Nephrology
• Missing data
• Surgery
Problem(s) • Failure to address missing outcome data in analyses
• Cochrane reviews more rigorous/higher quality than non-Cochrane reviews
Number of systematic reviews included 83
Summary of Findings From 17 Cochrane and 66 non-Cochrane systematic reviews of kidney transplant studies, the majority of systematic reviews did not quantify (90% [n = 60] non-Cochrane and 29% [n = 5] Cochrane) or include the reasons for missing participant data (88% [n = 58] non-Cochrane and 24% [n = 4] Cochrane). Eleven percent (n = 9) handled missing participant data, 5% (n = 4) justified the analytical method(s) used to handle it, and 2% (n = 2) performed a sensitivity analysis for it.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? N/A
Are the methods of the article described in enough detail to replicate the study? Yes