Tripterygium wilfordii Hook. f. Preparations for Rheumatoid Arthritis: An Overview of Systematic Reviews

Ref ID	883
First Author	H. Li
Journal	EVIDENCE-BASED COMPLEMENTARY & ALTERNATIVE MEDICINE: ECAM
Year Of Publishing	2022
URL	https://www.hindawi.com/journals/ecam/2022/3151936/
Keywords	Protocols Complimentary & Alternative Pre-specification Rheumatology Disclosure Musculoskeletal Low reporting quality Searching Low methodological quality
Problem(s)	Individual study characteristics not reported sufficiently Undocumented or unjustified deviations to the review protocol Insufficient literature searches Lack of prespecification in eligibility criteria Reasons for excluding potentially eligible studies not provided Conflict of interest statement or disclosures for review authors missing No registered or published protocol Low methodological (AMSTAR) quality
Number of systematic reviews included	27
Summary of Findings	From 27 included systematic reviews of sing Tripterygium wilfordii Hook. f. preparations in patients with rheumatoid arthritis indexed across The Cochrane Library, PubMed, Embase, VIP database, China National Knowledge Infrastructure, CBM, and WanFang up to July 13 2021. Out of the 27 included systematic reviews, 20 were rated critically low methodological quality (AMSTAR 2). 92.6% did not report a publicly available protocol and significant deviations from the protocol were found; 91.49% did not provide a list of excluded studies and justified the exclusions; 96.3% did not explain the selection of the study designs for inclusion in the review; 81.49% did not use a comprehensive literature search strategy; 66.67% did not report any potential sources of conflicts of interest; and 66.67% described the included studies insufficiently.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results?	Not Applicable
Are the methods of the article described in enough detail to replicate the study?	Yes