Tripterygium wilfordii Hook. f. Preparations for Rheumatoid Arthritis: An Overview of Systematic Reviews

Ref ID 883
First Author H. Li
Year Of Publishing 2022
Keywords Protocols
Complimentary & Alternative
Low reporting quality
Low methodological quality
Problem(s) Individual study characteristics not reported sufficiently
Undocumented or unjustified deviations to the review protocol
Insufficient literature searches
Lack of prespecification in eligibility criteria
Reasons for excluding potentially eligible studies not provided
Conflict of interest statement or disclosures for review authors missing
No registered or published protocol
Low methodological (AMSTAR) quality
Number of systematic reviews included 27
Summary of Findings From 27 included systematic reviews of sing Tripterygium wilfordii Hook. f. preparations in patients with rheumatoid arthritis indexed across The Cochrane Library, PubMed, Embase, VIP database, China National Knowledge Infrastructure, CBM, and WanFang up to July 13 2021. Out of the 27 included systematic reviews, 20 were rated critically low methodological quality (AMSTAR 2). 92.6% did not report a publicly available protocol and significant deviations from the protocol were found; 91.49% did not provide a list of excluded studies and justified the exclusions; 96.3% did not explain the selection of the study designs for inclusion in the review; 81.49% did not use a comprehensive literature search strategy; 66.67% did not report any potential sources of conflicts of interest; and 66.67% described the included studies insufficiently.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? Not Applicable
Are the methods of the article described in enough detail to replicate the study? Yes