- Framework of problems / Rigourous
- Conflicts of interest or funding of included studies not assessed
- Digital Biomarker-Based Interventions: Systematic Review of Systematic Reviews
| Ref ID | 892 |
| First Author | H. Motahari-Nezhad |
| Journal | JOURNAL OF MEDICAL INTERNET RESEARCH |
| Year Of Publishing | 2022 |
| URL | https://www.jmir.org/2022/12/e41042 |
| Keywords |
Publication bias Risk of bias Disclosure General medical Low reporting quality Searching Low methodological quality |
| Problem(s) |
Low methodological (AMSTAR) quality Risk of bias not incorporated into conclusions of review Conflicts of interest or funding of included studies not assessed Reasons for excluding potentially eligible studies not provided Insufficient literature searches Poor consideration of publication bias |
| Number of systematic reviews included | 25 |
| Summary of Findings | From 25 included systematic reviews with meta-analyses of clinical outcomes (efficacy and safety endpoints) of digital biomarker–based interventions compared with alternative interventions without digital biomarkers indexed across PubMed and the Cochrane Library between 2019-2020. Most reviews (23/25, 92%) had critically low methodological quality according to the assessment using AMSTAR-2. From the 25 reviews 92% did not report a comprehensive literature search or provide a list of excluded studies or funding sources. Only 7 reviews (28%) took risk of bias into account when reporting results and 13 (52%) did not carry out an adequate investigation of publication bias. |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Not Applicable |
| Are the methods of the article described in enough detail to replicate the study? | Yes |