Three out of four published systematic reviews on COVID-19 treatments were not registered and one-third of those registered were published: a meta-research study

Ref ID 910
First Author W. Siemens
Journal JOURNAL OF CLINICAL EPIDEMIOLOGY
Year Of Publishing 2022
URL https://www.sciencedirect.com/science/article/pii/S0895435622002323?via%3Dihub
Keywords • COVID
• Protocols
• Living
• Pre-specification
• Non-Cochrane reviews
Problem(s) • No registered or published protocol
Number of systematic reviews included 239
Summary of Findings From 239 included systematic review of COVID-19 treatments registered in PROSPERO and in the COVID-19 Living Overview of the evidence ( https://app.iloveevidence.com). A total of 71 of 239 PROSPERO protocols (29.7%) were published as full systematic reviews. In the LĀ·OVE sample, 261 of 346 systematic reviews (75.4%) were not registered in PROSPERO before publication.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? N/A
Are the methods of the article described in enough detail to replicate the study? Yes