- Framework of problems / Transparent
- Multiplicity of outcomes and lack of pre-specification for outcome reporting
- Substantial heterogeneity found in reporting mortality in Cochrane systematic reviews and Core Outcome Sets in COMET database
Ref ID | 913 |
First Author | E. Tomlinson |
Journal | JOURNAL OF CLINICAL EPIDEMIOLOGY |
Year Of Publishing | 2022 |
URL | https://www.sciencedirect.com/science/article/pii/S0895435622000142?via%3Dihub |
Keywords |
Cochrane Multiplicity Pre-specification Outcomes |
Problem(s) |
Multiplicity of outcomes and lack of pre-specification for outcome reporting Weaknesses identified in some Cochrane reviews |
Number of systematic reviews included | 1978 |
Summary of Findings | From 1978 included Cochrane systematic reviews that included mortality as an outcome published January 2015-March 2021. There were 2,454 mortality outcomes were reported in 49% (1978/3999) of Cochrane reviews: all-cause (37%), infant (23%), maternal (11%), survival (10%), cause-specific (9%). Due to reviews not specifying mortality outcome type or including studies reporting no data, 11% (273/2208) remained uncategorized. Infant mortality and maternal mortality were frequently used together in reviews reporting two mortality outcomes. |
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Not Applicable |
Are the methods of the article described in enough detail to replicate the study? | No |