- Framework of problems / Transparent
- Multiplicity of outcomes and lack of pre-specification for outcome reporting
- Outcomes in Cochrane systematic reviews related to wound care: An investigation into prespecification
| Ref ID | 92 |
| First Author | Z. Liu |
| Journal | WOUND REPAIR & REGENERATION |
| Year Of Publishing | 2017 |
| URL | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/wrr.12519?download=true |
| Keywords |
• Nursing • Pre-specification • Cochrane • Multiplicity |
| Problem(s) |
• Multiplicity of outcomes and lack of pre-specification for outcome reporting |
| Number of systematic reviews included | 106 |
| Summary of Findings | 106 protocols were included for systematic reviews with 126 outcome domains. Outcomes were frequently poorly prespecified. Method of aggregation was the most poorly specified element (76–100% unclear), and when specified, it was usually a “percentage/proportion.” Time points and metric were very poorly specified, except for the domain of wound healing. Primary outcomes tended to be more completely specified than secondary outcomes. |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | N/A |
| Are the methods of the article described in enough detail to replicate the study? | Yes |