Effectiveness of nonpharmacological interventions to prevent adverse events in the intensive care unit: A review of systematic reviews

Ref ID	923
First Author	S. Suclupe
Journal	AUSTRALIAN CRITICAL CARE
Year Of Publishing	2022
URL	https://dx.doi.org/10.1016/j.aucc.2022.11.003
Keywords	• Low methodological quality • Searching • General medical • Transparency • Protocols • Pre-specification • Harms
Problem(s)	• Insufficient literature searches • Lack of prespecification in eligibility criteria • Reasons for excluding potentially eligible studies not provided • No registered or published protocol • Low methodological (AMSTAR) quality
Number of systematic reviews included	37
Summary of Findings	From 37 included systematic reviews of nonpharmacological interventions for preventing adverse events in the intensive care unit, indexed across PubMed, CINAHL, and Cochrane Library up to March 2022. Twenty-eight of thirty seven (75.6%) systematic reviews scored critically low on methodological quality and six (16.2%) systematic reviews scored low. The main deficiencies noted were: 1) failure to report a prior registered protocol 2) adequacy of the literature search 3) justification for excluding studies 4) reasons for study design selection and 5) describing the included studies in adequate detail. None of the included systematic reviews fulfilled all the AMSTAR-2 criteria. Regarding the certainty of the evidence, only six (16.2%) systematic reviews reported the certainty of evidence for the primary outcomes.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results?	N/A
Are the methods of the article described in enough detail to replicate the study?	Yes