Effectiveness of nonpharmacological interventions to prevent adverse events in the intensive care unit: A review of systematic reviews

Ref ID 923
First Author S. Suclupe
Journal AUSTRALIAN CRITICAL CARE
Year Of Publishing 2022
URL https://dx.doi.org/10.1016/j.aucc.2022.11.003
Keywords Harms
Protocols
Transparency
Pre-specification
General medical
Searching
Low methodological quality
Problem(s) Insufficient literature searches
Lack of prespecification in eligibility criteria
Reasons for excluding potentially eligible studies not provided
No registered or published protocol
Low methodological (AMSTAR) quality
Number of systematic reviews included 37
Summary of Findings From 37 included systematic reviews of nonpharmacological interventions for preventing adverse events in the intensive care unit, indexed across PubMed, CINAHL, and Cochrane Library up to March 2022. Twenty-eight of thirty seven (75.6%) systematic reviews scored critically low on methodological quality and six (16.2%) systematic reviews scored low. The main deficiencies noted were: 1) failure to report a prior registered protocol 2) adequacy of the literature search 3) justification for excluding studies 4) reasons for study design selection and 5) describing the included studies in adequate detail. None of the included systematic reviews fulfilled all the AMSTAR-2 criteria. Regarding the certainty of the evidence, only six (16.2%) systematic reviews reported the certainty of evidence for the primary outcomes.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? Not Applicable
Are the methods of the article described in enough detail to replicate the study? Yes