Saturated fat, the estimated absolute risk and certainty of risk for mortality and major cancer and cardiometabolic outcomes: an overview of systematic reviews

Ref ID 931
First Author J.R. Talukdar
Journal SYSTEMATIC REVIEWS
Year Of Publishing 2023
URL https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-023-02312-3
Keywords • Low methodological quality
• Oncology
• Nutrition
Problem(s) • Unplanned or unjustified subgroup or sensitivity analyses
• Methods not described to enable replication
• Funding or sponsor of systematic review not reported
• Low methodological (AMSTAR) quality
Number of systematic reviews included 17
Summary of Findings From 17 included systematic reviews of saturated fat or fatty foods on the risk of mortality and major cancer and cardiometabolic outcomes in adults indexed across MEDLINE, EMBASE, CINAHL in the ten years leading to March 30, 2021. The methodological quality (AMSTAR-2) of two-thirds of the systematic reviews was critically low to moderate. The main limitations included deficient reporting of study selection, absolute effect estimates, sources of funding, and a priori subgroups to explore heterogeneity.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? N/A
Are the methods of the article described in enough detail to replicate the study? Yes