- Framework of problems / Transparent
- Selective reporting of harms / safety / adverse events / side effects
- More than one-third of systematic reviews did not fully report the adverse events outcome
| Ref ID | 377 |
| First Author | R. Parsons |
| Journal | JOURNAL OF CLINICAL EPIDEMIOLOGY |
| Year Of Publishing | 2019 |
| URL | https://www.jclinepi.com/article/S0895-4356(18)30816-3/pdf |
| Keywords |
Harms Protocols |
| Problem(s) |
Selective reporting of harms / safety / adverse events / side effects |
| Number of systematic reviews included | 1376 |
| Summary of Findings | Of the included review protocols of health care interventions in PROSPERO, only 38% listed adverse events as an outcome of interest. In a final cohort 146 published reviews 65% fully reported the adverse events outcome exactly as intended from the protocol. 8% of the reviews excluded the adverse effect outcome entirely. The remaining 27% at least partially reported adverse events or in some way changed the reporting of the outcomes. |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Not Applicable |
| Are the methods of the article described in enough detail to replicate the study? | Yes |