Selective reporting of harms / safety / adverse events / side effects

This problem is addressed in PRISMA 2009, PRISMA 2020 and MECIR. Systematic reviews may limit reporting of adverse events to the most common, most serious, determined to be caused by the intervention etc. But in this process the full safety profile is often not available in the final report of a systematic review.

Articles that support this problem:

More than one-third of systematic reviews did not fully report the adverse events outcome

2019 : Journal of clinical epidemiology

Reporting of adverse events in systematic reviews can be improved: survey results

2008 : Journal of clinical epidemiology

Availability of large-scale evidence on specific harms from systematic reviews of randomized trials

2004 : The american journal of medicine

The reporting of safety among drug systematic reviews was poor before the implementation of the PRISMA harms checklist

2019 : Journal of clinical epidemiology

Selective reporting bias of harm outcomes within studies: findings from a cohort of systematic reviews

2014 : Bmj

Methodological quality of meta-analyses on treatments for chronic obstructive pulmonary disease: a cross-sectional study using the AMSTAR (Assessing the Methodological Quality of Systematic Reviews) tool

2015 : Npj primary care respiratory medicine

Quality of reporting in systematic reviews of adverse events: systematic review

2014 : Bmj : british medical journal

Side effects are incompletely reported among systematic reviews in gastroenterology

2015 : Journal of clinical epidemiology

The Cochrane HPV vaccine review was incomplete and ignored important evidence of bias

2018 : Bmj evidence-based medicine

A systematic survey showed important limitations in the methods for assessing drug safety among systematic reviews

2020 : Journal of clinical epidemiology

Challenges in systematic reviews that assess treatment harms

2005 : Annals of internal medicine

Assessing the Reporting of Harms in Systematic Reviews Focused on the Therapeutic and Cosmetic Uses of Botulinum Toxin

2023 : Clinical drug investigation

Systematic reviews on the success of dental implants present low spin of information but may be better reported and interpreted: An overview of systematic reviews with meta-analysis

2022 : Clinical implant dentistry & related research

A cross-sectional analysis of harms reporting in systematic reviews evaluating laminectomy

2023 : North american spine society journal

Harms reporting by systematic reviews for functional endoscopic sinus surgery: a cross-sectional analysis

2023 : European archives of oto-rhino-laryngology

Harms Reporting Is Inadequate in Systematic Reviews Regarding Hip Arthroscopy

2023 : Arthroscopy, sports medicine, and rehabilitation

An analysis of harms reporting in systematic reviews regarding ketorolac for management of perioperative pain

2022 : British journal of anaesthesia

Assessing the Reporting and Frequency of Harms in Systematic Reviews Focused on Minimally Invasive Hysterectomies: A Cross-sectional Analysis

2023 : Journal of minimally invasive gynecology

Exercise across the Lung Cancer Care Continuum: An Overview of Systematic Reviews

2023 : Journal of clinical medicine