- Framework of problems / Comprehensive
- Poor consideration of publication bias
- Non-communicable diseases research output in the Eastern Mediterranean region: an overview of systematic reviews
| Ref ID | 419 |
| First Author | A. Akkawi |
| Journal | BMC MEDICAL RESEARCH METHODOLOGY |
| Year Of Publishing | 2020 |
| URL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082905/pdf/12874_2020_Article_924.pdf |
| Keywords |
Protocols Grey literature Error Publication bias Risk of bias Disclosure General medical Low reporting quality Searching Low methodological quality |
| Problem(s) |
No registered or published protocol Insufficient literature searches Reasons for excluding potentially eligible studies not provided Poor consideration of publication bias Conflicts of interest or funding of included studies not assessed Low methodological (AMSTAR) quality Funding or sponsor of systematic review not reported Conflict of interest statement or disclosures for review authors missing Single reviewer / lack of double checking Grey literature excluded No quality assessment undertaken or reported Risk of bias not incorporated into conclusions of review Errors in effect estimate calculations or data synthesis |
| Number of systematic reviews included | 89 |
| Summary of Findings | 83% of included reviews were of low AMSTAR quality and 1% was of high quality. Common flaws were: “a priori” design (13.5%); duplicate reviewer (21%); comprehensive literature search (20%); grey literature included (19%); list of excluded studies (3%); quality assessment (32%); quality incorporated into conclusions (21%); appropriate data synthesis (53%); publication bias assessed (16%); conflicts of interest assessed (0%). |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Not Applicable |
| Are the methods of the article described in enough detail to replicate the study? | Yes |