The appropriateness of asymmetry tests for publication bias in meta-analyses: a large survey

Ref ID 649
First Author J. P. Ioannidis
Journal CMAJ
Year Of Publishing 2007
URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839799/pdf/20070410s00015p1091.pdf
Keywords • Publication bias
• General medical
Problem(s) • Poor consideration of publication bias
Article Type Empirical
Article Subtype Cross-sectional survey/Methodological systematic review
First Author Country United States
Aim Aims to measure, in a survey of meta-analyses, how frequently the application of funnel plot tests for asymmetry would be not meaningful or inappropriate
Level of Investigation Descriptive
Summary of Findings In most meta-analyses, the application of funnel-plot asymmetry tests to detect publication bias is inappropriate or not meaningful.
Number of systematic reviews included 464
Number of eligible systematic reviews assessed 7719
Treatment impacted Yes
Treatment impacted description
Interpretation impacted No
Interpretation impacted description