Statistical controversies in clinical research: publication bias evaluations are not routinely conducted in clinical oncology systematic reviews

Ref ID 70
First Author D. Herrmann
Journal ANNALS OF ONCOLOGY
Year Of Publishing 2017
URL https://www.annalsofoncology.org/article/S0923-7534(19)31999-4/pdf
Keywords Publication bias
Oncology
Problem(s) Poor consideration of publication bias
Number of systematic reviews included 182
Summary of Findings From the 182 included systematic reviews sampled from the top five highest impact factor oncology journals published between 2007 and 2015 publication bias assessments were not frequently used in oncology systematic reviews. 40% of systematic reviews (73/182) discussed publication bias and 28% of reviews (51/182) included an assessment of publication bias. Conference abstracts were the most commonly reported form of gray literature, followed by clinical trials registries. Fifty-one reviews reported publication bias evaluations. The most common method was the funnel plot (80%, 41/51) followed by Egger’s regression (59%, 30/51) and Begg’s test (43%, 22/51).
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? Not Applicable
Are the methods of the article described in enough detail to replicate the study? Yes