Association between industry sponsorship and author conflicts of interest with outcomes of systematic reviews and meta-analyses of interventions for opioid use disorder

Ref ID 794
First Author S. Ferrell
Journal JOURNAL OF SUBSTANCE ABUSE TREATMENT
Year Of Publishing 2022
URL https://www.sciencedirect.com/science/article/pii/S074054722100324X?casa_token=-pmNQ951B7EAAAAA:mzYhL1CUB2jt_ftZp4Mc8KHSJHhkgfWsDUVQDQHRmpxeF269Itngxk3jZ8AXo7X_ptAX6Sy1qLw
Keywords Author
Pain
Allegiance
Sponsorship bias
Disclosure
Non-Cochrane reviews
Problem(s) Conflict of interest statement or disclosures for review authors missing
Non-financial conflicts of interest of review authors
Financial conflicts of interest of review authors
Number of systematic reviews included 17
Summary of Findings From 17 systematic reviews of opioid use published across 3 databases up to June 2 2020, 25 authors (30.9%) had some form of conflict of interest, and 22 (of 25, 88.0%) authors had an undisclosed conflict of interest. However, no significant association existed between conflicts of interest and favourability of results and conclusions. Notably, two systematic reviews (of 17; 11.76%) were industry-sponsored. No association was found between the study sponsor source and the favourability of systematic review results and conclusions.
Did the article find that the problem(s) led to qualitative changes in interpretation of the results? No
Are the methods of the article described in enough detail to replicate the study? Yes