- Framework of problems / Objective
- Financial conflicts of interest of review authors
- Association between industry sponsorship and author conflicts of interest with outcomes of systematic reviews and meta-analyses of interventions for opioid use disorder
| Ref ID | 794 |
| First Author | S. Ferrell |
| Journal | JOURNAL OF SUBSTANCE ABUSE TREATMENT |
| Year Of Publishing | 2022 |
| URL | https://www.sciencedirect.com/science/article/pii/S074054722100324X?casa_token=-pmNQ951B7EAAAAA:mzYhL1CUB2jt_ftZp4Mc8KHSJHhkgfWsDUVQDQHRmpxeF269Itngxk3jZ8AXo7X_ptAX6Sy1qLw |
| Keywords |
Author Pain Allegiance Sponsorship bias Disclosure Non-Cochrane reviews |
| Problem(s) |
Conflict of interest statement or disclosures for review authors missing Non-financial conflicts of interest of review authors Financial conflicts of interest of review authors |
| Number of systematic reviews included | 17 |
| Summary of Findings | From 17 systematic reviews of opioid use published across 3 databases up to June 2 2020, 25 authors (30.9%) had some form of conflict of interest, and 22 (of 25, 88.0%) authors had an undisclosed conflict of interest. However, no significant association existed between conflicts of interest and favourability of results and conclusions. Notably, two systematic reviews (of 17; 11.76%) were industry-sponsored. No association was found between the study sponsor source and the favourability of systematic review results and conclusions. |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | No |
| Are the methods of the article described in enough detail to replicate the study? | Yes |