- Framework of problems / Objective
- Financial conflicts of interest of review authors
- Do Author Conflicts of Interest and Industry Sponsorship Influence Outcomes of Systematic Reviews and Meta-Analyses Regarding Glaucoma Interventions? A Cross-sectional Analysis
| Ref ID | 797 |
| First Author | A. Wise |
| Journal | JOURNAL OF GLAUCOMA |
| Year Of Publishing | 2021 |
| URL | https://www.ingentaconnect.com/content/wk/jglau/2021/00000030/00000004/art00019 |
| Keywords |
Author Allegiance Sponsorship bias Disclosure Ophthalmology Non-Cochrane reviews |
| Problem(s) |
Conflict of interest statement or disclosures for review authors missing Financial conflicts of interest of review authors |
| Number of systematic reviews included | 26 |
| Summary of Findings | From 26 included systematic reviews of glaucoma indexed in MEDLINE and Embase between September 1, 2016 and June 2, 2020. 9 (35%) were conducted by at least 1 author with an undisclosed conflict of interest. Of those 9, 3 (33%) reported results favouring the treatment group, and 5 (56%) reported conclusions favouring the treatment group. Of the 17 systematic reviews with no conflicted authors, 1 (6%) reported results favouring the treatment group, and 2 (12%) reported conclusions favouring the treatment group. The Fisher exact tests demonstrated that these differences held a statistically significant association between author conflicts and the favourability of the reviews’ conclusions toward the treatment group (P=0.04). |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | Yes |
| Are the methods of the article described in enough detail to replicate the study? | No |