- Framework of problems / Comprehensive
- Poor consideration of publication bias
- Trends in systematic reviews of kidney transplantation: A 10-year analysis of the evidence base
| Ref ID | 907 |
| First Author | S. Salih |
| Journal | TRANSPLANTATION REVIEWS |
| Year Of Publishing | 2023 |
| URL | https://www.sciencedirect.com/science/article/pii/S0955470X23000137?via%3Dihub |
| Keywords |
• Non-Cochrane reviews • Protocols • Surgery • Publication bias • Nephrology • Low methodological quality • Risk of bias • Transparency |
| Problem(s) |
• No registered or published protocol • Low methodological (AMSTAR) quality • Reasons for excluding potentially eligible studies not provided • Poor consideration of publication bias • Limited quality assessment or no risk of bias • Individual study characteristics not reported sufficiently |
| Number of systematic reviews included | 454 |
| Summary of Findings | From 454 included systematic reviews of kidney transplantation identified from the Transplant Library from 01 January 2008 until 31 December 2018. Of the included 454 systematic reviews 70% of systematic reviews were identified as critically low methodological quality (AMSTAR 2), which increased in number over time. The systematic reviews did not score well for protocol registration (16.96%), documentation of excluded studies (24.45%) and reporting of publication bias (32.16%). Review authors did not discuss the risk of bias or carry out appropriate statistical tests to assess the risk of publication bias in 73.90% and 67.80% of systematic reviews, respectively. There was also poor reporting of the included study designs in 84.40% of systematic reviews. |
| Did the article find that the problem(s) led to qualitative changes in interpretation of the results? | N/A |
| Are the methods of the article described in enough detail to replicate the study? | No |